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KMID : 0389420060140020049
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Korean Journal of Stress Research
2006 Volume.14 No. 2 p.49 ~ p.52
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Psychosocial Stress Models in Rodents
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Kim Dae-Soo
Shin Hee-Sup
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Abstract
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Conventional animal models of stress including immobility or electrical foot shocks are far from real life. As psychosocial diseases are increasing in human, animal models for reflecting phycosocial stress have been focus and developed. Establishement of phsychosocial stress models using mouse, where transgenic technologies and inbred strains are available, allows us to study moelcular mechanisms underlying the pathogenesis of stress. This paper is a review of the phychosocial stress models including social isoaltion, social defeat, and innate fear model in mice.
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KEYWORD
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Social isolation, Social defeat, Innate fear, Mice
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